Finding the self by losing the self: Neural correlates of ego‐dissolution under psilocybin
Ego‐disturbances have been a topic in schizophrenia research since the earliest clinical descriptions of the disorder. Manifesting as a feeling that one’s “self,” “ego,” or “I” is disintegrating or that the border between one’s self and the external world is dissolving, “ego‐disintegration” or “dissolution” is also an important feature of the psychedelic experience, such as […]
Study: Psilocybin From Magic Mushrooms Plus Therapy Delivers Benefits Nearly Five Years Later
A new study adds support to claims that the psychedelic drug psilocybin, when combined with psychotherapy, can effectively treat depression and anxiety years after taking the drug. The research follows up on a 2016 study that tested the effects of a single-dose, one-time use of psilocybin combined with psychotherapy on depression and anxiety symptoms among […]
Long-term follow-up of psilocybin-assisted psychotherapy for psychiatric and existential distress in patients with life-threatening cancer
Abstract Background: A recently published randomized controlled trial compared single-dose psilocybin with single-dose niacin in conjunction with psychotherapy in participants with cancer-related psychiatric distress. Results suggested that psilocybin-assisted psychotherapy facilitated improvements in psychiatric and existential distress, quality of life, and spiritual well-being up to seven weeks prior to the crossover. At the 6.5-month follow-up, after […]
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety
Highlights Acute psychedelic effects are related to decreases in depression/anxiety. Increases in psychological flexibility fully mediate this relationship. Psychological flexibility should be examined in clinical trials with psychedelics. Abstract Prior research has shown that acute subjective psychedelic effects are associated with both spontaneous and intended changes in depression and anxiety. Psychedelics are also theorized to […]
The effects of psilocybin and MDMA on between-network resting state functional connectivity in healthy volunteers new
Perturbing a system and observing the consequences is a classic scientific strategy for understanding a phenomenon. Psychedelic drugs perturb consciousness in a marked and novel way and thus are powerful tools for studying its mechanisms. In the present analysis, we measured changes in resting-state functional connectivity (RSFC) between a standard template of different independent components […]
Exploring the effect of microdosing psychedelics on creativity in an open-label natural setting
Taking microdoses (a mere fraction of normal doses) of psychedelic substances, such as truffles, recently gained popularity, as it allegedly has multiple beneficial effects including creativity and problem-solving performance, potentially through targeting serotonergic 5-HT2A receptors and promoting cognitive flexibility, crucial to creative thinking. Nevertheless, enhancing effects of microdosing remain anecdotal, and in the absence of […]
Bad Trip vs. Hard Trip new
THERE IS NO SUCH THING AS A BAD TRIP (?) “There’s no such thing as a bad trip” is a concept that is rising in popularity among experienced drug users. However, I don’t subscribe to this concept. To me, there is such a thing as a bad trip and it is determined by how we choose to […]
Handpicked List Of The Best Psychedelic Books
If you’ve ever aimed to learn more, educate yourself and read expert’s personal experiences with psilocybin and microdosing… this article is for you! Since our goal is to spread the magic of psilocybin, we decided to share a handpicked reading list of the best psychedelic books made by the SoulCybin team. We’ve put together a […]