SoulCybin Moderator Hi Iris, as David and Samantha mentioned, most likely the SNRI you are taking decreased the effect of the Psilocybin, and it’s important to consider the risks of taking a ceremonial and Venlafaxine.
We will highly recommend you consult with a physician that works with both medicines to guide you in the safest way to do a macro dose while you are still taking a prescribed medication.
Microdosing might be a safer way to start working with this sacred medicine for you, but again please consult with a professional for proper guidance and support.